A new study reveals starting hormone therapy around the time of menopause is linked to a greater risk of breast cancer compared to starting it later on.
Several past studies have shown an increase in breast cancer risk among women who use hormonal therapy. However, few studies have examined the role that timing plays as a risk factor for this type of cancer.
Researchers from Oxford University analyzed data on 1.13 million women who were enrolled in the Million Women Study in the United Kingdom. The researchers estimated the adjusted relative risks of breast cancer in hormone therapy users and past users compared to non-users. They also compared women on different types of hormone therapy.
They found that women who started hormone therapy at the time of menopause were at a greater risk for developing breast cancer than those who started it later. "This pattern of risk was seen across different types of hormonal therapy, among women who used hormonal therapy for either short or long durations, and also in lean and in overweight and obese women," the authors wrote.
source: ivanhoe
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