Co-E1 NADH (ENADA): terrific energy booster

For the almost twenty years I’ve known him, Oz Garcia, Ph.D., my close friend (and superstar nutritionist to the stars), has sworn by a little-known supplement named ENADA, calling it the ultimate energy supplement.

“It’s one of the most rehabilitating supplements I’ve ever come across”, he told me.

ENADA has actually changed names and is now known as Co-E1 NADH. It’s an unwieldy name, but a terrific product. People who love it have called it “: biological rocket fuel”. A number of studies have shown that it can significantly improve at least four recognized symptoms of chronic fatigue syndrome, including unexplained tiredness, difficulty thinking, sleep disturbances, and headaches or sore throats.

Researchers at the Sleep-Wake Disorders Center, Weill Cornell Medical College, found that it significantly improved measures of cognitive performance following a night of total sleep deprivation. Athletes use Co-E1 NADH to increase muscular energy supply. My friend Oz uses it all the time before he goes running.


So what is this stuff, anyway? NADH is the reduced form of NAD (nicotinamide adenine dinucleotide), a coenzyme that plays a key role in the energy production of cells, particularly in the brain and central nervous system. The more NADH a cell has available, the more energy it can produce.

NADH participates in the cellular processes that generate ATP (adenosine triphosphate) from glucose (sugar). ATP is known as the “energy molecule” because it’s cellular fuel for your muscles. Co-E1 NADH may help people with chronic fatigue syndrome by triggering energy production through the generation of ATP. Some studies indicate it may improve mental and physical endurance, as well as cognitive performance, possibly by stimulating the cellular production of neurotransmitters.

Co-E1 NADH is available as a lozenge. Oz recommends starting with 2.5 mg upon waking, and increasing in increments of 2.5 mg to 5 mg, 7.5 mg, or 10 mg upon waking. You can also use it at different times of the day.
“Always start low and work up”, he advises.

You can also pop one in your mouth 30 minutes or so before athletic activity, or any time you need a little boost in mental energy.